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Richard P. Carmody's avatar

Have there been cases where switching from one beta blocker (Sotalol) to Metoprolol has triggered an autoimmune reaction? I believe that this happened to me almost six years ago and triggered a case of lichen planus in my gums that I am still dealing with after four laser treatments.

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David C. Kibbe's avatar

Hi, Bill. I love the example about discontinuing a beta blocker. It's in plain English and could have been useful to a great many patients. I'd like to add an historical note to this discussion. From roughly 2000 through 20076 I was the Director of the Center for Health Informatics at the American Academy of Family Physicians, my job being to encourage, support, and lead the adoption by family physicians in the country to adopt Electronic Health Record (EHR) technology in their practices. It was a successful campaign leading to the majority of AAFP members across the country using EHRs by the end of this period. One important aspect of this campaign, an important strategy, was that over time the data from these EHRs could be used to develop and sustain "best practices." The idea was that data aggregated from many hundreds of patient care records on many dozens of important diagnoses would lead to the intelligence needed for in-the-moment consultations with patients and to a national effort to establish evidence-based guidelines. THIS NEVER HAPPENED, although there were some notable attempts at several places around the country. There were several reasons why this never happened, and I won't describe them all in detail. However, it is worth noting, I believe, that the biggest roadblock to the development of artificial intelligence based on best practices and outcomes gathered from physician practices was that the HMO movement disintegrated, leaving the EHR technology to be taken over by hospitals and used to support billing, accounting, and collection of $$ rather than becoming a tool for accountable care.

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