The last post showed how stage 3 or 4 chronic kidney disease is present in ten percent of patients with prediabetes. That means that the chronic kidney disease (CKD) is not caused by the increased blood sugar in diabetes. The same molecular biology and epigenetics that causes CKD also causes diabetes.
Diabetes is due to loss of pancreatic cells that make insulin. CKD is due to the loss of the functional cells in the kidney. Heart failure is due to loss of pumping cells. Liver failure is due to the loss of liver cells. There is a simultaneous stimulation of scar tissue growth in each of these organs.
The common denominator in risk factor elevation and organ damage is excess oxidant production. Increased oxidants cause loss of functional organ cells via programmed cell death or apoptosis. Increased oxidants also stimulate scar formation. Insulin producing cells in the pancreas die because of increased oxidant production. It is the same with liver cells and heart muscle cells. Excess oxidant production causes high blood pressure, lipid abnormalities, and high blood sugar while producing more organ damage than those risk factors alone. It is important to use precision medications to treat those risk factors that protect cells and organs. Real whole foods have antioxidants in them. Diet, exercise, losartan, lisinopril, statins, metformin, spironolactone, eplerenone, and empagliflozin are all antioxidants that work to protect cells and organs.
Yup!
In addition, sugar is acting like a slow poison acting on the mitochondrial functioning by reducing ATP formation leading to mitochondrial hibernation and eventual death, similar to Cyanide poisoning.