Occam’s Razor “…of two competing theories, the simpler explanation of an entity is to be preferred.” Other than the minority of chronic illnesses caused by single gene mutations, most chronic disease and aging comes from this core epigenetic signaling pathway outlined in the diagram above. Genes that are essential to fetal development, become much less active in healthy young adults, and are reactivated chaotically later in life to accelerate aging and chronic disease development. That fundamental understanding makes protocol design and training much easier. Of course, the diagram above is the most basic to show the core mechanisms and the treatments in the green boxes that interfere precisely with these mechanisms.
The diagram below shows more detail, and there is more and more complexity beyond that, but the simple diagram above provides basic understanding. A system based on risk factors and organ systems is out of date. We can delay chronic diseases and slow aging by directly addressing the biology that causes both in every cell and every organ. Please let me know if you have questions and I really appreciate your comments.
The “more detailed one” missed the impact of fasting and exercise wittingly or unwittingly, sad!