Sitemap - 2021 - Slow Aging and Delay Chronic Disease Development

Better Cardiovascular Care for Women: It's a Matter of Life or Death!

Slow Aging and Delay Chronic Disease: Introduction and Directory

A Very Simple Lesson in the Language of Childhood Development, Chronic Disease, and Aging

No, She Did Not Need Prozac!

Women With Stable Heart Artery Disease Are Different!

When I First Saw Her, It was Heavy Lifting

She Cried on the Second Visit

She Taught Me About Relationship and Listening

High Touch Matters: Longitudinal Trusting Relationships are Critical for Patients with Chronic Disease

Like Metformin, Eplerenone, and Losartan, Empagliflozin Switches Off mTOR and Switches On SIRT1 and AMPK

Like Eplerenone and Metformin, Losartan is a Precision Medicine

It Is Time to Think Differently About Aldosterone and Eplerenone

Metformin Blocks ADMA to Switch Off mTOR and Switch on AMPK

Increased ADMA Levels Cause Insulin Resistance and Arterial Damage: Metformin Blocks ADMA

Processed Foods Combining Fat and Carbs Acutely Increase ADMA and Decrease Arterial Dilation in 5 Hours

Arginine, ADMA, Metformin: Three of the Most Important Relationships in Biology

ADMA and Chronic Kidney Disease

ADMA-Metformin Antagonism: A Critical Element in Aging and Chronic Disease

Hey administrators: You Can’t Solve a Clinical Problem by Providing an Administrative Solution!

Metformin: A Completely New Mechanism of Action

Stopping Statin in Elderly Results in More Heart Attacks and Strokes

SGLT2 Inhibitors Tied to Fewer Atrial Arrhythmias

The Best Leader I Knew from WWII

This Entire Site Supports You in Achieving Optimal Medical Treatment for Cardiovascular Disease

Quality Is a Systems Property

You Can Help!

An Infantry Officer Taught Me About Leadership

Repeated Chest Pain in Women Means Higher Heart Attack Risk

Tactics Lag Technology: People Struggling with Diabetes in Your Community Could Live Eight Years Longer

Tactics Lag Technology: Especially in Medical Quality

Tactics Lag Technology: Most Patients Don't Receive Optimal Medical Therapy (OMT) for Their Type 2 Diabetes

Tactics Lag Technology: The Diabetes Example

Check Out Yesterday's Post

My Son Taught Me This Valuable Lesson: Tactics Lag Technology

Metformin Mimics Fasting by Blocking the Nutrient Sensing Mechanism of mTOR

Many Learned Enough About the Antioxidant Vitamin E to Take It but It Did Not Work

Your Family Can Have Better Health At Lower Cost Now!

None of His Male Family Members Lived Past 45

The Most Important Statin Study in Type 2 Diabetes

Interpreting Our Key Diagram

"How Our Current Healthcare System Fails Patients with Type 2 Diabetes"

Statins Switch on AMPK and Increase Nitric Oxide Production

Ochsner Saved $100,000,000 treating 30,000 Medicare Advantage Patients

Now We Can Do Something About Heart Failure (CHF) with Preserved Ejection Fraction

Optimal Medical Treatment (OMT) Reduces Heart Failure Admissions by 70% Over a Twenty-one-year Period

Optimal Medical Therapy and Heart Failure with Preserved Ejection Fraction (HFpEF)

Relationships Required to Translate the New Science and Systems.

Care for Congestive Heart Failure is Still Awful

Lower Glucose Targets Are Important, but Not at the Expense of Hypoglycemia

Statins Block Coenzyme Q10 (CoQ10) Production

Practical Measures to Prolong Healthy Life Now

It is not Just Lowering the Risk Factor That Matters

Metformin Directly Inhibits the Same Master Metabolic Switch as the Drug in Modern Stents

The Same Gene Networks Cause Heart Disease and Cancer

A Practical Approach for Long-lasting Weight Loss

Save Your Vision with Optimal Medical Treatment (OMT)

People with Type 2 Diabetes on Metformin Live Longer than Non-diabetics.

Increased Abdominal Fat Causes Chronic Disease

Cigarette Smoke Switches on EGFR to Cause Cancer and Emphysema

Why The First Dot Is So Important

The Article That Connected the Dots

She Had a Heart Attack and Her Arteries Were Wide Open!

Heart Disease Kills Ten Times as Many Women as Breast Cancer!

One Third Of Women Who Die of Heart Artery Disease Have Minor Blockage

Women Are Different: Especially When it Comes to Heart Disease!

Pancreatic Cancer is Increasing

Lower Carbs, Lower sugar!

OMT Protects Orthopedic Surgery Patients with Diabetes

Carbohydrate Restriction as First Intervention in Diabetes

Switching on AMPK Favors Weight Loss

Aging and Enlarged Heart

Poor Diet, Excess Weight, and Autism

Adverse Childhood Experiences (ACEs) Lead to Chronic Diseases

Precision Management for Congestive Heart Failure

mTOR and AMPK Play a Critical Role in Heart Enlargement

Bone In the Artery

Diabetes Drug Reduces Heart Failure Admissions in Patients With Preserved Pumping Function

Oxidants Drive Mental and Physical Frailty

Your Fluid Pill Choice Matters!

You Can Do This!

Pick Losartan Instead of Lisinopril

Oxidants and Alzheimer's Disease

Aging and Virtually All Chronic Diseases Are Related

Oxidants and Rheumatoid Arthritis

Major Life Stesses, Depression, and Cardiovascular Disease

New Insights in Osteoporosis

EGFR Plays a Critical Role in Cartilage Metabolism.

Oxidants Are a Key Driver of Osteoarthritis

Metformin Slows Cartilage Loss in Osteoarthritis

Tying It All Together!

Aspirin Prevents Deaths from Preeclampsia

High Insulin Levels Increase All-cause Death

Optimal Medical Treatment Reduces All Cause Death by Half at Ten Years

EGFR Plays a Key Role in the Most Common Skin Cancer

EGFR and Oxidants Are Critical Cancer Regulators

Only One Identical Twin Gets Breast Cancer. Why?

How An Oncologist Would Treat Her Own Melanoma

Aspirin Inhibits mTOR and Activates AMPK

Clinical Trials of Medications are Short

An Optimal Medical Therapy Miracle?

Humans on Metformin Have Smaller Heart Attacks

A Single Dose of Metformin Cuts Heart Attack Size in Half

High Insulin Levels Make Us Fatter, Older, and Sicker

Dogma Derails the Science of Obesity

Enjoy Healthier, Longer Life Now!

Higher ADMA Levels Are An Independent Predictor of Death In the Elderly

1-Updated Introduction and Directory: Posts 2 through 43 Help You Produce Optimal Medical Treatment (OMT) Consistently

ADMA and Metformin Are Virtually Identical

ADMA Blocks Nitric Oxide Production

Nitric Oxide (NO) is the Active Ingredient From Nitroglycerin and Viagra

Lifestyle and Medicine  Extend Healthy Life Through the Same Biology

Exercise Prolongs Life and Delays Chronic Disease

Antioxidant Supplements Provide No Value

4-Updated: Stents Provide No Additional Benefit to Optimal Medical Treatment for Heart Artery Disease

Food as Poison: Sugar

Food as Medicine: Dried Beans

Food as Medicine: Olive Oil

Research Has Never Shown That Insulin Prolongs Life In Type 2 Diabetes

Other Growth Factors Can Substitute in the EGFR Position in Cancer

The Epidermal Growth Factor Receptor (EGFR) is Another Master Metabolic Switch

A Very Simple Lesson in the Language  of Childhood Development, Chronic Disease, and Aging

Tobacco Smoke Contains Ten to the Fifteenth Oxidative Particles per Puff

The New Science of Pancreatic Cancer

New Science About the Cause of Type 2 Diabetes

3-Updated: Better Care is Less Expensive Care in Heart Artery Disease

Rapamycin is an Antibiotic That Leaks Slowly from a Heart Artery Stent to Decrease Scar, Inflammation, and Keep the Stent Open: Metformin Does that in all Your Arteries!

If Begun Within 90 Days of a Heart Attack or a Stent, Optimal Medical Treatment Lowers Heart-related and All-Cause Death by 90%!

1-Updated Introduction and Directory: Posts 2 through 43 Support You in Producing Optimal Medical Treatment Consistently

Calorie Restriction, Intermittent Fasting, Exercise, Lisinopril, Losartan, Statins, Metformin, Spironolactone, and Jardiance All Impact the Same Biology to Prolong Healthy Life

Vitamin E Did Not Work as An Antioxidant: Lisinopril, Losartan, Statins, Spironolactone, and Metformin are Antioxidants That Improve Health and Reduce Costs

Singapore Only Spends 5% of Gross Domestic Product on Healthcare, We Spend 18%!

Prior to the Pandemic, Medical Care Was the Number One Concern of Voters

More Diabetics Die In the US than Europe in Part Because Most American Providers Don't Use Protocols.

The US Mortality Rate for Diabetes Is 42% Higher Than in Other Developed Countries

My Own Heart Story

Spine, Knee Cartilage, and Heart Surgery Often Provide No Benefit: Best Practice Non-Invasive Treatments are Better

Exercise With Weights and 15 Repititions to the Point of Fatigue Best Preserves Strength and Function as We Age.

You Can't Outrun a Spoon!

Some Companies Say They Can Reverse Diabetes: They Can’t!

Fraud Made You Fat!

Two Thirds of the Calories Eaten by American Children Come From Highly Processed Foods and the Percentage is Increasing

Optimal Medical Treatment First is the Standard of Care for Leg Artery Disease

Half the Patients who Have a Procedure to Open a Leg Artery Are Dead Within 2.7 Years!

ACE Inhibitors Like Lisinopril and ARBs Like Losartan Reduce Your Risk of Becoming Diabetic

Metformin Reduces Heart Attack Risk by 40% in Type 2 Diabetes for $4 a Month

Children with Type 2 Diabetes Develop Complications at a Very Young Age

Statin Treatment Cuts the Risk of Heart Attack in Half in the Real World When Properly Taken

Medicare Advantage: A Key to Value in Healthcare

Most Quality Improvement is Unsuccessful: The Heart Failure Example

Especially For The Ladies: If You Have Repeated Chest Pain, You Need Optimal Medical Treatment (OMT)

Now American Cardiology Guidelines Support Optimal Medical Treatment First: It is so Easy!

Five Percent of American Adults Have a Cardiac Stress Test Each Year for $11 Billion: It is Almost All Waste!

Guidelines are Not Enough: How Can We Move Quickly to Optimal Medical Treatment for Heart Arteries?

A Great Example of Why We Spend Twice as Much on Healthcare and Don’t Live as Long!

Heart Artery Stent Use Has Not Decreased Despite Proof They Don't Help in Stable Patients

Despite Compelling Evidence Proving Heart Artery Stents Do Not Prevent Death or Heart Attack in Stable Patients, Their Use Has Declined Very Little Since 2010

Getting Stronger Quickly After no Exercise During the Pandemic

The Deck is Stacked Against Value-based Healthcare.

Low Potassium Levels Caused by Fluid Pills are Dangerous and Easily Avoided

Optimal Medical Treatment is Important After a Heart Artery Blockage is Opened.

Even if They Lose Weight, Overweight Teens are More Likely to Develop Diabetes and Heart Disease Later.

Nurse Practitioners are Great!

A New Dawn for Obesity Treatment

Statins, Aging, Multiple Meds (polypharmacy) and Stopping Meds (deprescribing)

Ovarian Cancer: It’s Personal

Two Master Metabolic Genetic Switches Play a Central Role in Chronic Disease and Aging

Type 2 Diabetes: The Huge Disconnect Between Evidence and Performance

Use Slow Aging and Delay Chronic Disease Development More Effectively

Valsartan Alone is as Good as Valsartan Sacubitril (Entresto) in Advanced Heart Failure

A New Arrow in the Precision Medicine Quiver for Cardiovascular Disease

He Needed Elective Surgery: Just Not a Knee Replacement

Best Practice Medical Treatment Pays Huge Dividends in Heart Artery Disease

Gene Editing to Lower Cholesterol

Over Half the Medicare Patients Who Have a Procedure to Open a Blocked Leg Artery Are Dead Within Three Years

Do You Really Know What You are Getting Into?

A Great Example of the Difference Between Usual Care and Optimal Medical Treatment

The Best Introduction to Epigenetics: The Main Cause of Most Chronic Disease

COVID Made Me Weaker Even Though I Never Had the Disease

The Pancreas is the First Organ to Fail in Type 2 Diabetes

Inflammation in Chronic Disease: Moving from an Organ-based System to a Broader View

More Practical Uses for Rapamycin

Expanding Dr. Kenyon's Story on Aging

Brief, Entertaining Video on Slowing Aging

51- Data and Chronic Disease

Updated Introduction and Directory

51. Video: ChenMed Podcast on Optimal Medical Therapy

50-Your Perfect Grandchild, Radiation Injury, and the Language of Life

My Personal Story Update

49- Definitive Article on Blood Pressure Control in the AHA Journal Hypertension: The Huge Disconnect Between Usual Care and Optimal Medical Therapy

48- Update on Aspirin: A Critical Component of Optimal Medical Therapy

47- Precision Medicine, Big Data, and the Future of Medicine

My Story

46- Better Care is Less Expensive Care: The COVID Vaccine Example

45- Make the Right Way the Easy Way: Optimal Medical Treatment in High Blood Pressure

44- Make the Right Way the Easy Way: Optimal Medical Treatment in Type 2 Diabetes

43- Summary: A Unifying Hypothesis of Chronic Disease and Accelerated Aging

42-Heart Failure Treatment

41- Heart Failure Treatment

40-Congestive Heart Failure

39- Medical Science Has Advanced Just as Fast as Telephone Science

38- Almost All Chronic Diseases and Accelerated Aging Have a Common Origin

37-Critical Videos for Understanding Cardiovascular Disease and Related Conditions

36- Know YOUR Risk of a Heart Attack

35-Subscriber Stories about Heart Disease

34- Bringing It Altogether

33- Too much Insulin Accelerates Aging and Chronic Disease Development

32- The Second Medicine in the Protocol for Type 2 Diabetes

31- Metformin- Precision Medicine for Type 2 Diabetes

30-Treatments for High-Risk Type 2 Diabetes

29- Treatments for Type 2 Diabetes Different in Lower Risk Patients

28- Eleven Simple Steps to Blood Pressure Control

27- Prescription vs “Natural” Drugs

26- The Most Underused Medicine for High Blood Pressure and Related Conditions

25-How Our Current Healthcare System Fails Patients with High Blood Pressure

24- A Deeper Understanding of High Blood Pressure Treatments

23- Control Your High Blood Pressure Easily

22- A Deeper Understanding of Type 2 Diabetes Treatments

21- New Science of Type 2 Diabetes

20-How Our Current Health Care System Fails Patients with Diabetes

19-Diabetic Retinopathy and Macular Degeneration

18- Diabetic Kidney Disease-You Probably Don't Know you Have It!

17- A Simple Checklist  to Control High-Risk Type 2 Diabetes

16- A Message to Mothers in Diabetic Families

15- Type 2 diabetes is a food disease

14- Optimal Medical Treatment for Type 2 Diabetes

13- Prediabetes

12- Optimal Medical Treatment (OMT) Pays Huge Dividends in Patients with Type 2 Diabetes

11- Heart Artery Disease Summary

10-Personal Stories About Chronic Disease

9- The Language of Life, Death, Aging, and Chronic Disease

8-Exercise to Lower Cardiac Risk

7-Especially For Women

6-The Most Important Lifestyle Adjustment is Food

5-Optimal Medical Treatment for Heart Artery Disease and Heart Attack

4-Updated: Stents Add Nothing to Optimal Medical Treatment for Heart Artery Disease

3-Updated: Better Care is Less Expensive Care in Heart Artery Disease

1-Updated Introduction and Directory: Posts 2 through 43 Support You in Producing Optimal Medical Treatment Consistently

2-You can slow accelerated aging and delay chronic disease with a few simple steps. You can have better health at lower cost with less fuss