Sitemap - 2022 - Slow Aging and Delay Chronic Disease Development
Celebrating Our Second Anniversary
Guidelines Recommend Statin Therapy in all Patients with Diabetes
More on the Consolidated Appropriations Act from Jeff Hogan
Self-insured Employers: Don't Ignore the Consolidated Appropriations Act (CAA)
Saturated Fat Switches on mTOR Leading to Chronic Kidney Disease
Olive Oil Ingredients Switch on AMPK and Switch off mTOR
More on the Health Effects of Extra Virgin Olive Oil and the Mediterranean Diet
The Shortest Summary of the New Science and Systems to Slow Aging and Chronic Disease
The Rest of the Story: Other Medicines That Switch Off mTOR and Switch on AMPK
ADMA and Metformin: The Key to the mTOR-AMPK Interaction
New Research Advances the ADMA-Metformin Story in Diabetes and Related Diseases
The Better Way Extends to Other Chronic Diseases
A Better Way to Treat Type 2 Diabetes and Related Diseases
Preeclampsia, ADMA, and Metformin
34 years: That's How Long We Have Known that Heart Artery Stents Don't Work in Stable Patients!
Preeclampsia is Like Other Cardiovascular Disease
California Crosses the Quality Chasm In Maternal Mortality
California Reduced Maternal Mortality to Levels Seen in Other Developed Countries
Better Nutrition for Poor People: Let’s Light a Candle!
Understanding Aging: We Don’t Wear Out. We Rust Out.
Small Vessel Disease and Dementia
The New Science of Aging and Chronic Disease: Shortest Summary
Treating Widespread Microvascular Disease
Another Unifying Hypothesis: Microvascular Disease is A Whole Body Condition
Two Podiatrists and an Internist Talk About Saving Legs
He Had a Normal Nuclear Stress Test and Died the Next Day of a Heart Attack
Poor Blood Pressure Control Can be Easily Fixed
A Blood Pressure Target of 120 for the Top Number Lowered CV Events and Death by One Fourth
Our Healthcare System Fails Patients with Hypertension
Overeating Causes Excess Oxidant Production and Insulin Resistance Acutely
It is Not Just the Mothers Who Die
Another Way the US Health System Fails Women
Medical Costs are Extremely High in the US: We Could Do Something About that Now!
Organ Damage and Risk Factors are Caused by the Same Molecular Biology and Epigenetics
Ten Percent of Individuals with Prediabetes and Undiagnosed Diabetes Have Chronic Kidney Disease
You May Not Live Longer, but it Will Definitely Seem Longer
Progression of Chronic Kidney Disease is Not Inevitable
Jeff Hogan on Better Healthcare Purchasing for Employers
If Buying a House Were Like Self-funded Healthcare
The Most Important Healthcare Legislation Since the Affordable Care Act
Some Leaders Are Delivering Value but They Are Not Being Rewarded
One Word Describes Medical Pricing: Crazy!
Our Healthcare System is Characterized by Huge Amounts of Waste
Our Healthcare System Has High Rates of Preventable Care-associated Patient Injury and Death
Our Healthcare System Has High Rates of Inappropriate Care
Squeezing Out Variation in Chronic Illness Management
Successful Chronic Disease Management Requires a Comprehensive Solution
Patients with Type 2 Diabetes on Metformin and Empagliflozin Lose More Weight
Metformin Produces Weight Loss
The Role of the Primary Care Provider in Disease Prevention and Management in a Value-Based World
Optimal Medical Therapy (OMT) Lowers All-cause Mortality in Patients with Heart Artery Disease
We Found Another Woman With Repeated Chest Pain
How Our Approach to the Patient with Multiple Chronic Diseases is Different
Our Improved Approach to Population Health Management
Many Chronic Diseases are Related: Osteoarthritis
It's Time For Employers To Bring Health Care Decisions In-House
Thousands of Children in Some Zip Codes Suffer From PTSD
A Pharmaceutical Industry that Serves Americans Better
You Cannot Depend on Data or Advertising From Big Pharma
The Role of the Primary Care Provider in Disease Prevention and Management in a Value-Based World
CPC+ Model Has Not Controlled Costs or Quality on Private Side
Women with Repeated Chest Pain, Nurse Practitioners, and the Multifunction Cardiogram
Guideline and Policy Support for Optimal Medical Therapy (OMT)
Are You Serious About Moving to A Value-based Healthcare System?
Efforts to Reduce Healthcare Costs in America Almost Universally Fail
Return on Investment for Optimal Medical Therapy
Medications Like Spironolactone and Eplerenone are Underused
Blocking Aldosterone Improves Cardiovascular Risk Precisely
Use Spironolactone or Eplerenone When Prescribing Thiazide Diuretic
Finerenone Slows Chronic Kidney Disease Progression Precisely
Special Operations Primary Care Teams for Chronic Disease Management
For Patients: Chronic Kidney Disease
More Material to Support You in Producing Optimal Medical Therapy (OMT) Consistently
Fatty Liver: The Most Common Liver Disease
The Poor Elderly are Much Higher Risk
Rank Order of the Most Common Conditions in Medicare Patients
Moving to Value in Connecticut Through Industry Collaboration
Most Value-based Payment Programs in Medicine Fail
Another Kind of Precision Medicine
Optimal Medical Therapy: Let's Take the Weekend Off!
Cigarette Smoking Shortens Your Life by 10 Years and Makes You Sick Sooner
Other Medications Slow Aging and Delay Chronic Disease
Lower Your Insulin Level: Medication
Lower Your Insulin Level: Lifestyle
Carb Intake, High Insulin Levels and Increased Waist Size are a Vicious Cycle
Your Insulin Level Is Very High If Your Waist is Big
Insulin is Like Goldilocks' Porridge. It Needs to Be Just Right
Forget About Botox Injections, Facelifts, and Spider Vein Treatments
Intermittent Fasting: More Weight Loss and Increased Health Benefit
The Drug Price Negotiation Provisions Passed by the Senate This Week
The Case for Optimal Medical Therapy
Singapore: The Most Effective and Efficient Healthcare System in the World.
European and British Cardiology Guidelines Call for Optimal Medical Therapy First
Another Big Expense My Family Doesn't Need
The British Have Access to Optimal Medical Therapy Everywhere for Heart Artery Disease
Are You Struggling to Make Ends Meet?
Spread the Word on Optimal Medical Therapy for Arterial Disease
You Can Make a Difference in Diabetes Care!
Minnesota and Optimal Medical Therapy for Diabetes and Arterial Disease
The National Academy of Medicine (NAM) Blueprint for the Healthcare Revolution
The Four Simple Quality Measures that Matter in Arterial Disease
The Greatest Opportunity in American Medicine
Why Should I Be Held Accountable for What My Patient Does?
What is Optimal Medical Therapy (OMT)?
The Benchmark for Optimal Medical Therapy in Diabetes is 60%. The National Average is 20%.
Introduction to Continuing Medical Education (CME) Credits for Optimal Medical Therapy Training
The Five Quality Measures That Matter for Diabetes
It is not Diet or Exercise Alone for a Longer Healthier Life: Both Are Required
Expensive Heart Devices With No Proof of Effectiveness or Safety
Interventions to Slow Aging and Delay Chronic Illness
Statins Slow Aging and Delay Chronic Illness
Angiotensin II and Aldosterone Accelerate Aging and Chronic Illness Development
I Had Very High Blood Pressure: My Job Required World Travel
Information for Patients: Most People with High Blood Pressure Should Have a Goal of 130/80
My Sugar Was Very High and I Felt Terrible
Optimal Medical Treatment for Diabetes Changed My Life
Information for Patients: Chronic Kidney Disease
Optimal Medical Therapy in Small Towns: The Central Role of Nurse Practitioners
Information for Patients: Statins are Very Important to Prevent Heart Attack
Primary Care Provides Most Diabetes Care
American Healthcare Finance: More Detail on a Broken System
Nir Barzilai on Metformin and Aging
Seriously Ill Patients: A Canary in the Coal Mine for Medicare Advantage?
The Definitive Article on Type 2 Diabetes Improvement from Health Affairs
How Much Health Insurers Pay for Everything is About to Go Public
Refractory Late Life Depression, Accelerated Aging, and Cardiometabolic Comorbidities
There is a 17-year Gap Between New Science and It's Adoption in Clinical Practice
Lifestyle Intervention Improves Frail Older Adults’ Mobility
The NID-2 Study Validates Steno-2 and Optimal Medical Therapy (OMT) for Type 2 Diabetes
Italian Study Validates Steno-2 Findings in Patients with High-risk Type 2 Diabetes
Mental and Physical Health are Related at the Level of Epigenetics and Molecular Signaling
New Government Regulations Lower the Nicotine in Cigarettes
The Good Ol' Boys Are At It Again!
Cost is the Greatest Barrier to Good Healthcare in the United States
At Risk Primary Care Groups will Grow
Aldosterone Blockade Slows CAD and CKD and Blocks the Metabolic Syndrome
This Article Shows How Blocking Aldosterone Protects Cells and Organs
Spironolactone and Eplerenone are Dramatically Underprescribed
Secondary Hyperaldosteronism: A Common Complication of Blood Pressure Management
Information for Patients: Food is the Most Important Consideration in Type 2 Diabetes
Atrial Fibrillation, Dementia, and Smoking Cessation
The Egg That Made Me Formed in My Grandmother's Womb 100 Years Ago
Information for Patients: You Don't Have to Die of a Heart Attack!
Information for Patients: Don't Fall for Sugar Free
Information for Patients: You Can Live a Longer Healthier Life Now
A Physician Shoots Down my Position on Nurse Practitioners Managing Chronic Disease
Vaping Produces Roughly the Same Level of Oxidative Stress As a Cigarette
Information for Patients: Make Sure Your Blood Pressure is Low Enough to Protect You!
Huge Steps Backward in Hospital Quality and Price for Medicare Patients
County Governments Should Own and Support Outpatient Primary Care Chronic Disease Clinics
Information for Patients: Research that Proves a Medical Treatment Works
We Must Learn to Disrupt Ourselves: Innovation in Outpatient Primary Care
Information for Patients: Blood Pressure is Like Automobile Tire Pressure
Multiple Concurrent Crises in American Healthcare
We All Have a Stake in Better, Earlier Management for Type 2 Diabetes
The "Problems" with Medicare Advantage
The Headline: Metformin Fails to Benefit Breast Cancer Patients
Medicare Moving Toward Value-based Care
Only 1% of Heart Failure Patients Receive Optimal Medical Therapy at Appropriate Doses
Optimal Medical Therapy (OMT) Reduces Heart Failure Admissions by 70%
Community-owned Primary Care Clinics Manned by Nurse Practitioners
Federal Investigators Find Medicare Advantage Plans Too Often Deny, Delay Needed Care
Psychiatric/Mental Health Nurse Practitioners and the Cardiometabolic Team
Abbvie's Eye-popping Lobbying Keeps My Wife's Humira Cost High
Better Care for Chronic Kidney Disease is Less Expensive Care
White Male Obstetricians Used Abortion to Eliminate Midwives
American Nurse Practitioner Midwives Can Save Lives while Dramatically Reducing Costs
Medicare Spending on Prescription Drugs Far Outpaces Development Costs: This is Personal
Introduction to Independent Nurse Practitioners in Adult Health and Gerontology
Optimal Medical Therapy is Much More Powerful Than Praluent (alirocumab) in Preventing Heart Attack
Big Insurer Anthem Took in $38 Billion in the First Quarter of 2022: Mostly From Taxpayers
Practical Leadership in Cardiovascular Disease: The Chronic Kidney Disease Example
Leadership to Consistently Deliver the Quadruple Aim
A Practical Plan to Deliver the Quadruple Aim in Your Primary Care Practice Consistently
She Had a Heart Attack, But Her Heart Arteries Were Wide Open
We Will Never Achieve the Quadruple Aim in A Fee-For-Service Healthcare System
The Great Resignation in Healthcare: Nurse Practitioners are an Important Part of the Answer!
Better Health at Lower Cost in Allergic Conditions
Aldosterone Excess Increases Blood Pressure, Anxiety,and Depression
Substack is a Great Site for Reliable Health Information: Slow Aging and Delay Chronic Disease
There is a 17-year Gap Between New Knowledge and Practice: In Cardiovascular Disease it is 34 Years.
This Signaling Diagram Adds Your Understanding of Chronic Kidney Disease Prevention
The Reason Optimal Medical Therapy is So Effective in Preventing Dialysis in Diabetic Patients
The Number of Americans with End-stage Kidney Disease More than Doubled in 20 Years
Aspirin: Now Even that is Confusing!
A Physician Shoots Down my Position on Nurse Practitioners Managing Chronic Disease
Rural, Minority Americans Have Amputations and Die More Frequently from Diabetic Foot Ulcers
The American Medical Association: A Barrier to Longer Healthier Life at Lower Cost!
The Same Gene Networks Cause Heart Disease and Cancer
Healthcare Finance: A Huge Barrier for Independent Nurse Practitioners in Outpatient Primary Care
An Internist Promotes Nurse Practitioners and Pharmacists to Manage Chronic Illnesses
Nurse Practitioners in New York Achieve Independent Practice Status
Optimal Medical Therapy Achieves The Promise of Value-Based Care
Life Expectancy is Dropping More in The US than Other Countries
Severe Pancreatic Damage is Already Present in Prediabetes.
Metformin Reduces Stroke Damage by Switching on AMPK and Increasing Nitric Oxide Production
Another Close Female Friend with Repeated Chest Pain
He Had Dementia After Heart Artery Bypass Surgery
We Both Needed a Population Health Tool.
The Pancreas is the First Organ to Fail in Type 2 Diabetes
A Change in Symptoms Means a Change in Treatment
A Roadmap for Crossing the Quality Chasm in Chronic Disease
When Will We Finally Cross the Quality Chasm?
We Could Learn Something From the British
The Seeds of Early Heart Attack and Stroke are Sown in Childhood
Sun-Exposed Skin Is Older Than Your Other Cells and Organs: Accelerated Aging You Can See!
Dietary Carbohydrate Restriction as the First Approach in Diabetes Management: Evidence Base
Dietary Carbohydrate Restriction as the First Approach in Diabetes Management: Evidence Base
Tim Noakes is a Serious Runner who Gained 40 Pounds and Developed Diabetes
People I Care About Continue to Get Poor Medical Advice About Heart Artery Disease
Digging a Bit Deeper into Tactics Lag Technology in Healthcare
American Medical Quality Improvement Is Upside Down and Backwards
My Son Taught Me This Valuable Lesson: Tactics Lag Technology
Your Primary Care Team Can Manage Stable Heart Artery Disease without A Cardiology Referral
Interventions to Slow Aging in Humans: Are We Ready?
Aging is Regulated by Classic Signaling Pathways
New Private Optimal Medical Therapy Group on Facebook
It Seemed Like She Was 30: It Turns Out She Was 60!
Building on My Story: Large Cell Lymphoma Fits the Chronic Illness Model
Aging and All Chronic Diseases are Related
The Epidermal Growth Factor Receptor (EGFR) in Fetal Development, Cancer, and Vascular Diseases
The Article That Connected the Dots
Only One Identical Twin Gets Breast Cancer-Why?
Ban Advertising Juice and Cereal With Added Sugar During Children's TV Programing
Health Disparities in Chronic Kidney Disease (CKD)
Sodas with Sugar Substitutes have a Benefit on Weight and Risk Factors Similar to Drinking Water
Optimal Medical Therapy is Much More Effective Than Usual Care
A Single Small Dose of Metformin Reduces Heart Attack Size in Animals
You Can Lose Weight and Keep it Off Pretty Easily
Resistance Exercise is Critical to Longer Healthy Life
Critical Metformin Effects Beyond Lowering the Sugar
The Paradoxes of Women with Heart Disease
The NIH-Sponsored WISE Study Started in 1996
Jean Needed Optimal Medical Therapy
A Reason Heart Disease in Women is Different
Women with Repeated Chest Pain, And An Update From My Neighbor Jean
Weight Loss at a Community Level
The Same Gene Networks Cause Heart Disease and Cancer
This Specific NIH-Sponsored Study Shows Women with Repeated Chest Pain Are Different!
A Patient Can Get The Entire Base Optimal Medical Therapy Protocol for $36
It is More About Molecular Biology than the Target Risk Factor- The Heart Failure Example
You Can’t Rely on Industry-sponsored Research on Evidence-based Treatments for Chronic Disease
Independent Nurse Practitioners Can Lead the Way to Better Heart and Diabetes Care
Slow Aging and Delay Chronic Disease: Introduction and Directory
Blindness Due to Diabetes is a Systems Problem
The New Science That Shows How Optimal Medical Therapy Prevents Blindness from Diabetes
We Could Prevent More Blindness at Lower Cost in Diabetes
Dr Ron Donelson Makes the Case for Optimal Medical Therapy for Musculoskeletal Conditions
If Your Community Has Clean, Safe Water, You Can Have Optimal Medical Therapy
Diabetic Retinopathy is the Leading Cause of Adult Blindness in the United States.
Patients on Optimal Medical Therapy Have 1/3 as Many Amputations as Patients in Usual Care
The Founder: What is, and What Could Be!
% Optimal Medical Therapy Achievement: The Most Critical Quality Measure in Cardiovascular Disease
Optimal Medical Therapy is a Product: This Site Exists to Define, Update, Spread, and Support It.
Increased Abdominal Fat Causes Chronic Disease Directly
How Does Smoking Cause All These Seemingly Unrelated Diseases
Better Health at Lower Cost in Rural and Minority Communities by 2024
Medical Madness: Doing the Same Thing and Expecting a Different Result
By ACC Guideline, Optimal Medical Therapy First is the New Standard of Care for Stable Angina
As Kidney Function Declines, Risks and Costs Increase: OMT Increases Kidney Function
Health care costs rise Exponentially with Each Stage of Chronic Kidney Disease
How Our Healthcare System Fails Patients with Chronic Kidney Disease
ChenMed: Primary Care That Improves Health and Saves Money with Value-Based Payment
Bring Better Cardiovascular Care at Lower Cost to Your State or Community Now!
Nurse Practitioners Can Lead the Way to Better Cardiovascular Disease Management
The Medicare Prescription Drug, Improvement, and Modernization Act Prohibited Drug Price Negotiation
Autoimmune Diseases Like Psoriasis Increase Risk of Heart Attack
My Wife’s Illness, Medicare, and Negotiated Drug Prices
The Occam’s Razor of Chronic Diseases and Aging
The United States Does Not Provide the Best Care for Heart Artery Disease
It Happened Again Friday Night: Connecting the Dots in Alzheimer’s Disease
Milton Packer on the New Approach to Chronic Illness
New Hope for Heart Failure with Preserved Pumping Function
Normal Genes are Essential for Healthy Development: They Cause Chronic Disease Later in Life
ADMA: One Explanation for the Difference in Heart Artery Disease Between Women and Men
ADMA: One Explanation for the Difference in Heart Artery Disease Between Women and Men
Buyer Beware: Demand Evidence that Healthcare Product Improves Health and Reduces Cost
30 Years Ago, I Weighed 307 Pounds: 20 Years Ago I Was Prediabetic
No Advertisement, No Corporate Support, No Conflicts of Interest
Clearing Up the Confusion Around the Best Fourth Medication For a High Blood Pressure Protocol
You Can Easily Control Hypertension in 90% of Your Patients!
A Broken Healthcare System, Some Lights in the Darkness, and Affirmation from George Lundberg
Health Affairs: Only 40% of North Americans Trust Information from Healthcare Workers
You Can Be Healthier Longer Now and It Is Fairly Easy to Get There: Understanding the Science
Mary O'Connor on Promoting Health and Making a Documented Difference in Your Community
Cardiometabolic Medications That Inhibit mTOR Might Help Prevent or Treat Cancer
Must Hear TED Talk: Dr. Paula Johnson on Disconnect Between Research and Practice in Women!
Women with Repeated Chest Pain and No Blockage Generate $767,288 in Lifetime Healthcare Costs
Women with Repeated Chest Pain, My Neighbor Jean, and the Multifunction Cardiogram (MCG)
Optimal Medical Treatment Lowers Heart Failure Admissions by 70%: Why is it Not Available?
Reducing Readmissions in Congestive Heart Failure
Adverse Childhood Events, Culture, and Racism
There is a 17-year Gap Between New Science and Practice: In Cardiology it is Twice That!
Saving Lives In Rural Areas: We Can Do Much Better Now!
The Prince of Tides and Adverse Childhood Events
My Dramatic Introduction to One of the First Precision Medicines
More Deaths at Higher Cost from Heart Artery Disease in US Compared with Europe