Do we know how much metformin is effective for its anti aging property. Does one need a full 500mg/day dose? Will 250 mg suffice to achieve pro AMPK activity?
Most think of metformin as a glucose-lowering medicine. I think it impacts the key signaling pathways at lower doses. I have prediabetes and I take 500mg twice a day. I have no side effects at all.
Do we know how much metformin is effective for its anti aging property. Does one need a full 500mg/day dose? Will 250 mg suffice to achieve pro AMPK activity?
Most think of metformin as a glucose-lowering medicine. I think it impacts the key signaling pathways at lower doses. I have prediabetes and I take 500mg twice a day. I have no side effects at all.
https://www.nature.com/articles/s41586-022-04431-8
I do not have prediabetes. I hope to persuade my PCP to order it for me. We shall see as it would be for an “off label” indication.
That makes sense. Good luck
Amazing and thank you for discussing this topic.
The promise of new scientific discoveries is amazing. Thanks for your help