Elevated ADMA levels and increased oxidants are strong predictors of chronic kidney disease progression. Metformin blocks ADMA effects and in the real world it dramatically reduces disease progression and death in chronic kidney disease patients. Over 13 years, only one sixth as many patients with diabetic chronic kidney disease on an optimal medical therapy protocol containing metformin progressed to dialysis. Don’t you agree we should be using dose-adjusted metformin in stage 3 chronic kidney disease patients?
ADMA and Chronic Kidney Disease
ADMA and Chronic Kidney Disease
ADMA and Chronic Kidney Disease
Elevated ADMA levels and increased oxidants are strong predictors of chronic kidney disease progression. Metformin blocks ADMA effects and in the real world it dramatically reduces disease progression and death in chronic kidney disease patients. Over 13 years, only one sixth as many patients with diabetic chronic kidney disease on an optimal medical therapy protocol containing metformin progressed to dialysis. Don’t you agree we should be using dose-adjusted metformin in stage 3 chronic kidney disease patients?