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Vinnie's avatar

Would you ask AI Dr. Bill how this same issue could be controlled using readily available all natural substances such as High Dose Ascorbic Acids and such? (This way Bill is teaching a person to help themself) and held ask the correct questions from a practitioner if this is a choice!

- Wondering what Dr. Bill would suggest....

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William H Bestermann Jr MD's avatar

That is a very important question and it applies to other "all natural substances." Humans have used natural products containing metformin for hundreds of years.

While metformin is indeed derived from compounds found in Goat's Rue ( Galega officinalis, also known as French Lilac), it is a specific, purified chemical entity with well-defined properties and a specific chemical structure. The "biguanide produced by Goat's Rue or French Lilac" refers to a mixture of naturally occurring compounds, including various guanidine derivatives, not just pure metformin.

Here's a breakdown of the key differences:

1. Chemical Specificity and Purity:

Metformin: Is a single, well-defined chemical compound (dimethylbiguanide hydrochloride). Its production involves a specific chemical synthesis process to yield a pure substance with a consistent molecular structure and dosage.  

Biguanides in Goat's Rue: Goat's Rue contains a variety of guanidine derivatives, including galegine and other related compounds. While these compounds have blood glucose-lowering effects, they are not a single entity like metformin. The concentration and composition of these compounds can vary depending on the plant's growing conditions, harvest time, and preparation method.

2. Dosage and Standardization:

Metformin: As a pharmaceutical drug, metformin has precisely controlled dosages in tablet or liquid form. This ensures patients receive a consistent and predictable amount of the active compound.

Goat's Rue Preparations: Herbal preparations of Goat's Rue (teas, extracts, supplements) will have varying and often unstandardized concentrations of the active biguanide compounds. It's difficult to determine the exact amount of glucose-lowering substances a person is consuming, leading to inconsistent effects and potential safety concerns.

3. Safety and Efficacy:

Metformin: Has undergone extensive scientific research and clinical trials to establish its efficacy in treating type 2 diabetes and its safety profile. Dosage guidelines and potential side effects are well-documented.  

Goat's Rue: While traditional use suggests blood glucose-lowering properties, there is less rigorous scientific evidence to support its efficacy and safety compared to pure metformin. The other compounds present in the plant extract might have different pharmacological effects or potential toxicities that are not fully understood. Historically, some early biguanide derivatives from Goat's Rue were found to be too toxic for widespread use.

4. Regulatory Oversight:

Metformin: As a pharmaceutical drug, metformin is subject to strict regulatory oversight by health authorities (like the FDA in the United States). This ensures quality control, manufacturing standards, and proper labeling.  

Goat's Rue Preparations: Herbal supplements containing Goat's Rue are generally not subject to the same level of scrutiny as pharmaceutical drugs. Quality and purity can vary significantly between different products and manufacturers.

5. Historical Context:

Metformin's Development: Metformin was specifically synthesized and isolated based on the observation that compounds in Goat's Rue had glucose-lowering effects. Researchers aimed to find a safer and more effective specific compound.  

Early Biguanides: Early attempts to use crude extracts or other biguanide derivatives from Goat's Rue were often limited by toxicity. Metformin was found to have a better safety profile than some of its predecessors like phenformin and buformin, which were eventually withdrawn from the market in many countries due to the risk of lactic acidosis.

In summary: Metformin is a purified and well-characterized drug that was developed based on the glucose-lowering properties observed in Goat's Rue. However, the plant itself contains a mixture of compounds, and using unstandardized preparations of Goat's Rue is different from taking precisely dosed and regulated metformin. While the historical link is important, they are not interchangeable in terms of predictable therapeutic effect and safety.

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Vinnie's avatar

LOL I see you blocked my response regarding the fact that AI/Dr. Bill's comments which did NOT accurately represent the benefits of naturally occurring solutions.

As we can see it provided a comparison between Metformin and Goat Rue or something...

Sorry, someone mis-informed Dr. AI./ Bill.

It did NOT accurately or honestly answer my query, as we all know and what has been scientifically proven

Naturally:

For STARTERS:

Clean Diet, ( low carb)

Clean real foods

(No processed foods)

High Dose Liposomal Vitamin C

Liver support

Milk Thistle

Lemon Juice

And

Benfotamine

All aid in slowing/ controlling Diabetes...

Other than

Metformin

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Vinnie's avatar

Tell Dr. Bill I was not asking for a comparison as to the difference between a chemical compound and naturally occurring compound.

Also , what load need Vitamin C and the health of the liver and pancreas have in aiding or stabilizing diabetes.

What role does adjustment to diets play and what role excluding highly processed foods and processed seed oils Do in benefitting pancreas and liver processing?

It is still promoting metformin...

IMHO THERE MUST be a natural resolution to this problem.

I insist because my entire family on both sides have this.

One group has relieved all symptoms through lifestyle control, the other uses those metformin drugs etc.

you will never guess which relatives are healthier, drug and disease free...

Or will you?

Cheers!!!

Thanks very much for taking the time!!

Dr. Bill seems still a shill! 🤣👋

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Apr 10
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William H Bestermann Jr MD's avatar

I apologize. It has recently been increased to $9 a month.

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William H Bestermann Jr MD's avatar

It is $4 a month at Walmart and $10 for three months. That is the cash price without any insurance. Walmart has many inexpensive generics and that can be a great help.

https://i5.walmartimages.com/dfw/4ff9c6c9-119c/k2-_c3e2f451-7a63-414e-aac2-e3defc13ef60.v1.pdf

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