This very short and entertaining TED talk by Dr. Cynthia Kenyon examines the molecular biology of extending healthy life. A mutation in the daf-2 gene in a small worm doubles the healthy lifespan of that animal. In humans, the insulin and IGF-1 genes correspond to the daf-2 gene in C. elegans. That has very practical implications for your health.
Many Americans begin eating sugar and processed carbs when they get up and they don’t stop until they go to bed. That results in increased weight and resistance to the effects of insulin. Sugar and processed carbs raise the insulin level. Insulin resistance requires an even higher insulin level to keep the blood sugar level normal. Many Americans therefore live with insulin levels that are three times those of a healthy, slender adult on a balanced diet. That accelerates aging and chronic disease development. Reducing sugar and carb intake and taking those carbs in a whole grain form reduces insulin levels and should prolong healthy life. Insulin is a growth factor that activates the same signaling as EGFR to contribute to chronic disease development.
The bottom line: immediately following puberty, and growth phase, a person should eat one meal a day to live longer.
Thank you for this. It is a real eye opener for many people who do not realize what they are doing daily.