Dr. Milton Packer, a world-renowned cardiologist and congestive heart failure expert, has called for a fundamental change in the way we think of chronic disease: “…it is now critical for physicians to reconceptualize SGLT2 inhibitors (like Jardiance) as organ-protective agents rather than glucose-lowering drugs.” That same idea can be extended to lisinopril, losartan, statins, metformin, and eplerenone which also protect every organ and cell in the body while slowing aging. What do you current and future medical leaders think? How long will it take to start moving in this direction?
Natural occurring endogenous Beta-Hydroxybutyrate produced during fasting or ketogenic style eating may have a broad regulatory role in metabolic disease through alterations in histone acetylation and gene expression, post-translational protein function, and cell surface receptor activation. Endothelial cellular repairs may involve BHB. Stem cell activation may involve BHB, etc., etc., and etc. better than ALL these drugs, Bill.
I am going to have to disagree with you on this one. Our recent medical history is riddled with treatments that were adopted because they made sense, but they failed to produce the expected results on human health. You know the best example only too well. We are still opening arteries in patients with stable heart artery disease. This entire site is devoted to promoting treatments that are proven to extend healthy life and reduce cost in humans. It is not just a question of which single intervention is the best, but what combination of interventions directly interfere with the biology that causes chronic disease and aging. I have also worked hard to explain why these interventions are better at the level of genetics, epigenetics, and molecular biology. Unless an intervention is proven to improve human health and lower cost, I am not in favor of it. There is a mountain of evidence supportaing OMT. That is the core intervention. The right study is to look at OMT with or without BHB. If we then have proof it helps humans live healthier longer and saves money, then we have something to talk about.
Of course, needless to say. The evidenve on BHB is pretty solid. Unbiased and honest side by side cmparison wothout any corrupt practice is the way to go. It needs to be done for ALL our sakes. Besides, these agents actually "mimic" the benefitial effects of fasting per the authors. Fasting triggers ketogenisis, BHB is a huge part of this process.
Natural occurring endogenous Beta-Hydroxybutyrate produced during fasting or ketogenic style eating may have a broad regulatory role in metabolic disease through alterations in histone acetylation and gene expression, post-translational protein function, and cell surface receptor activation. Endothelial cellular repairs may involve BHB. Stem cell activation may involve BHB, etc., etc., and etc. better than ALL these drugs, Bill.
I am going to have to disagree with you on this one. Our recent medical history is riddled with treatments that were adopted because they made sense, but they failed to produce the expected results on human health. You know the best example only too well. We are still opening arteries in patients with stable heart artery disease. This entire site is devoted to promoting treatments that are proven to extend healthy life and reduce cost in humans. It is not just a question of which single intervention is the best, but what combination of interventions directly interfere with the biology that causes chronic disease and aging. I have also worked hard to explain why these interventions are better at the level of genetics, epigenetics, and molecular biology. Unless an intervention is proven to improve human health and lower cost, I am not in favor of it. There is a mountain of evidence supportaing OMT. That is the core intervention. The right study is to look at OMT with or without BHB. If we then have proof it helps humans live healthier longer and saves money, then we have something to talk about.
Of course, needless to say. The evidenve on BHB is pretty solid. Unbiased and honest side by side cmparison wothout any corrupt practice is the way to go. It needs to be done for ALL our sakes. Besides, these agents actually "mimic" the benefitial effects of fasting per the authors. Fasting triggers ketogenisis, BHB is a huge part of this process.