A new article in JAMA points to these relationships. Late life depression (LLD) is more likely to be resistant to treatment, associated with dementia, and with a higher burden of physical illness. Treatment failure leads to persistent depressive symptoms, depleted psychological well-being, increased disability, accelerated dementia, and increased mortality in older adults. Risk factors for LLD include cardiovascular risk factors (eg, metabolic syndrome), cerebrovascular disease, brain structural changes, physical comorbidity, and frailty. It seems that LLD may have specific mechanisms that are associated with age-related brain and systemic processes.
Absolutely! Here is something to think about:
https://youtu.be/9-RU87qXOdQ