The last two posts have been about the complications of diabetes, high blood pressure, and high cholesterol and their relationship to genes that are abnormally switched on. When I had completed my cancer treatment for diffuse large cell lymphoma, I weighed 307 pounds, and I was six feet and two inches tall. The picture above was taken at about that time. Then, the
I totally agree with that. Nutrition is the root cause absolutely and you can absolutely prevent diabetes. Absolutely. Diabetes, heart failure, and chronic kidney disease are on the rise because we changed what we eat. Since we stopped eating real food 60 years ago, there are 10 times as many type 2 diabetics as there were then. If we just ate real, whole food that would make a big difference. Lean meat, eggs, seafood, fruit, vegetables, beans, peas, and nuts. Big food combines fat, salt, sugar, and carbs to make food that is addictive. People like me can't stop eating it.
Your voice is important. You understand the critical role of food. When we eat this addictive food it produces increased abdominal fat that switches on genes in the fat that cause increased blood pressure, high cholesterol, and insulin resistance. They cause increase oxidant production that increases inflammation and kills the functional cells in organs like the pancreas, kidney, and heart. It is all related and it requires a comprehensive strategy to protect us. But you are right. Diet is the root cause. You are obviously a very smart guy and you can easily learn enough to know how to protect yourself and those you care about.
Thanks for sharing, Bill. From my years of independent data mining experience developing our technology, I truly believe that if we early and accurately detect the metabolic heart dysfunction and urge the evidence-based data-driven lifestyle optimization measures to reduce or reverse the early signs of diabetes, most people will respond and do much better, less likely to develop these chronic diseases. These do NOT have to be our destiny.
The reality is that the crony medical industrial complex and its sponsored public and private institutions pay little attention to the early detection and primary disease prevention research. A paltry 2.5% of the research funds are allocated to this effort. They placate the masses in order to gaslight and plunder through a diabolical system of late-stage sickness-seeking profiteering schemes since WWII. Imagine that!
Watch the documentary From Food to Freedom (https://www.youtube.com/watch?v=nDLirbCGCcw), and also Plant Pure Nation (https://www.youtube.com/watch?v=yBKnG9Y0owQ&t=51s) -- I have seen results for dozens of these 10- or 21-day "jumpstart" programs, and the overall experience is that in many cases A1C can be normalized in as little as three weeks on a whole foods, plant-based diet, and even faster when combined with water fasting (https://www.truenorthhealthfoundation.org/). 95+% of T2D can be reversed in a period of 3 weeks to 3 months. I am friends with an MD who did 10+ 10-day jumpstarts just prior to Covid, Across the board 20% improvements in BP, Triglicerides, A1C, and Cholesterol in even a 10-day program are normal, and frequently meds need to be adjusted. In a 21-day program many insulin-dependent diabetics can be off insulin altogether. The bottom line is, the compliance is high, because there are only good side effects, no adverse side effects, as Dr. Dean Ornish has frequently commented.
This is a real problem. It reflects a misunderstanding of the latest science on diabetes. Sure, you can get the sugar down to a normal number, but the risk of high sugar switches on genes that cause premature death heart attack and stroke and these epigenetic changes persist even when risk factors go back down. Oxidant production remains high. That is why patients need medication to block the excess oxidant production from these epigenetic changes. You can lower the glucose but you cannot reduce the risk without medication that blocks the excess oxidant production.
I appreciate the feedback, but you are now above my paygrade. I tend to think however that the nutritional problem is primary. It drives everything else, and we could eliminate 80% of pharmaceutical drugs, particularly all the "blockbuster" drugs which invariable target the chronic illnesses that are all caused by nutrition and lifestyle. Speaking of which, I am off to the gym now ;-)
The story of pouring Insulin to deal with established Type II diabetes is misguided. Too much and too frequent Insulin causes chronic illnesses, high blood pressure, coronary artery disease, cancer, immune deficiency, etc. Sadly, we have OVER DONE ourselves.
You make a great point. Insulin is a growth factor that switches on mTOR and switches off AMPK. The medications that dramatically improve outcomes switch off mTOR and switch on AMPK. That is why outcomes are so much different.
Read T. Colin Campbell's China Study, and his more recent Future of Nutrition. Consider consulting with True North Health, Dr Alan Goldhamer. Whole Foods, Plant-Based nutrition is the way to go, plus waterfasting. I switched to a new PCP this year, but I consult with True North. When my new doc saw my results, instead of them telling me what to do, they asked me how I did it.
Thanks. I think it is important to give everyone the tools to validate my conclusions. Now we have applied this in a real work site clinic. Patients seen in the clinic cost half as much as those seen in the community. They are hospitalized one fifth as often and in the ER one third as often. It works.
Thank you Dr. Bestermann. Your experiences and knowledge and esoecially the details help all of us. So thrilled you are still here after your tough health journey.
I have heard of the Warburg effect and the microenvironment that is essential to tumor growth. Optimal medical therapy dramatically reduces all cause mortality and perhaps that is part of it
I totally agree with that. Nutrition is the root cause absolutely and you can absolutely prevent diabetes. Absolutely. Diabetes, heart failure, and chronic kidney disease are on the rise because we changed what we eat. Since we stopped eating real food 60 years ago, there are 10 times as many type 2 diabetics as there were then. If we just ate real, whole food that would make a big difference. Lean meat, eggs, seafood, fruit, vegetables, beans, peas, and nuts. Big food combines fat, salt, sugar, and carbs to make food that is addictive. People like me can't stop eating it.
Your voice is important. You understand the critical role of food. When we eat this addictive food it produces increased abdominal fat that switches on genes in the fat that cause increased blood pressure, high cholesterol, and insulin resistance. They cause increase oxidant production that increases inflammation and kills the functional cells in organs like the pancreas, kidney, and heart. It is all related and it requires a comprehensive strategy to protect us. But you are right. Diet is the root cause. You are obviously a very smart guy and you can easily learn enough to know how to protect yourself and those you care about.
https://www.aarp.org/entertainment/books/info-05-2009/why_we_eat_too_muchinterview_with_david_kessler_author_of_the_end_of_overeating_taking_control_of_the_insatiable_american_appetite.html
Good interview, passing this on also. TY!
Thanks for sharing, Bill. From my years of independent data mining experience developing our technology, I truly believe that if we early and accurately detect the metabolic heart dysfunction and urge the evidence-based data-driven lifestyle optimization measures to reduce or reverse the early signs of diabetes, most people will respond and do much better, less likely to develop these chronic diseases. These do NOT have to be our destiny.
Right!! We don't have to be sick or fat. There are good, common sense approaches that make a huge difference.
The reality is that the crony medical industrial complex and its sponsored public and private institutions pay little attention to the early detection and primary disease prevention research. A paltry 2.5% of the research funds are allocated to this effort. They placate the masses in order to gaslight and plunder through a diabolical system of late-stage sickness-seeking profiteering schemes since WWII. Imagine that!
It is past time to change our system to improve health and reduce costs.
As Rob Lustig put it: “We have been running a fifty-year wild goose chase, at least.” I agree.
Several stakeholders have come together to provide an alternate solution.
https://williamhbestermannjrmd.substack.com/p/taking-the-first-steps-with-health
Watch the documentary From Food to Freedom (https://www.youtube.com/watch?v=nDLirbCGCcw), and also Plant Pure Nation (https://www.youtube.com/watch?v=yBKnG9Y0owQ&t=51s) -- I have seen results for dozens of these 10- or 21-day "jumpstart" programs, and the overall experience is that in many cases A1C can be normalized in as little as three weeks on a whole foods, plant-based diet, and even faster when combined with water fasting (https://www.truenorthhealthfoundation.org/). 95+% of T2D can be reversed in a period of 3 weeks to 3 months. I am friends with an MD who did 10+ 10-day jumpstarts just prior to Covid, Across the board 20% improvements in BP, Triglicerides, A1C, and Cholesterol in even a 10-day program are normal, and frequently meds need to be adjusted. In a 21-day program many insulin-dependent diabetics can be off insulin altogether. The bottom line is, the compliance is high, because there are only good side effects, no adverse side effects, as Dr. Dean Ornish has frequently commented.
This is a real problem. It reflects a misunderstanding of the latest science on diabetes. Sure, you can get the sugar down to a normal number, but the risk of high sugar switches on genes that cause premature death heart attack and stroke and these epigenetic changes persist even when risk factors go back down. Oxidant production remains high. That is why patients need medication to block the excess oxidant production from these epigenetic changes. You can lower the glucose but you cannot reduce the risk without medication that blocks the excess oxidant production.
https://williamhbestermannjrmd.substack.com/p/metabolic-memory-and-epigenetics
https://williamhbestermannjrmd.substack.com/p/oxidants-metabolic-memory-and-chronic
I appreciate the feedback, but you are now above my paygrade. I tend to think however that the nutritional problem is primary. It drives everything else, and we could eliminate 80% of pharmaceutical drugs, particularly all the "blockbuster" drugs which invariable target the chronic illnesses that are all caused by nutrition and lifestyle. Speaking of which, I am off to the gym now ;-)
The story of pouring Insulin to deal with established Type II diabetes is misguided. Too much and too frequent Insulin causes chronic illnesses, high blood pressure, coronary artery disease, cancer, immune deficiency, etc. Sadly, we have OVER DONE ourselves.
You make a great point. Insulin is a growth factor that switches on mTOR and switches off AMPK. The medications that dramatically improve outcomes switch off mTOR and switch on AMPK. That is why outcomes are so much different.
Yup. Someone has to share the truth.
Read T. Colin Campbell's China Study, and his more recent Future of Nutrition. Consider consulting with True North Health, Dr Alan Goldhamer. Whole Foods, Plant-Based nutrition is the way to go, plus waterfasting. I switched to a new PCP this year, but I consult with True North. When my new doc saw my results, instead of them telling me what to do, they asked me how I did it.
There is no other methodology that improves on these outcomes over 5-21 years
https://pubmed.ncbi.nlm.nih.gov/20973686/
https://www.nejm.org/doi/full/10.1056/nejmoa0706245
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506099/#:~:text=Conclusions%2Finterpretation,free%20from%20incident%20cardiovascular%20disease.
Thank you for these links.
Thanks. I think it is important to give everyone the tools to validate my conclusions. Now we have applied this in a real work site clinic. Patients seen in the clinic cost half as much as those seen in the community. They are hospitalized one fifth as often and in the ER one third as often. It works.
Thank you Dr. Bestermann. Your experiences and knowledge and esoecially the details help all of us. So thrilled you are still here after your tough health journey.
Thank you. My purpose is to give you a practical path that is easy and inexpensive. It helps to know that it has value to some of you.
I really appreciate you sharing your experience. Thank you!
Thank you. It is good to know it helps
I guess you heard of the warburg effect so cutting out sugars could also lower the chances of the cancer returning!
I have heard of the Warburg effect and the microenvironment that is essential to tumor growth. Optimal medical therapy dramatically reduces all cause mortality and perhaps that is part of it
Hope you find this link useful https://www.fightaging.org/